diff --git a/cpu/nrf5x_common/Makefile.dep b/cpu/nrf5x_common/Makefile.dep
index 7c54a45a71..13fa0087ab 100644
--- a/cpu/nrf5x_common/Makefile.dep
+++ b/cpu/nrf5x_common/Makefile.dep
@@ -10,3 +10,7 @@ USEMODULE += cpu_common
 FEATURES_OPTIONAL += vdd_lc_filter_reg1
 # reg0 feature denotes stage 0 two-stage regulator models
 FEATURES_OPTIONAL += vdd_lc_filter_reg0
+
+ifneq (,$(filter nimble,$(USEPKG)))
+  USEPKG += nrfx
+endif
diff --git a/pkg/nimble/Makefile b/pkg/nimble/Makefile
index ee32f8a689..991ca45d6c 100644
--- a/pkg/nimble/Makefile
+++ b/pkg/nimble/Makefile
@@ -38,7 +38,7 @@ nimble_porting_nimble:
 	$(QQ)"$(MAKE)" -C $(PDIR)/porting/nimble/src/ -f $(RIOTPKG)/$(PKG_NAME)/nimble.porting.mk MODULE=$@
 
 nimble_npl_riot:
-	$(QQ)"$(MAKE)" -C $(PDIR)/porting/npl/riot/src/ -f $(RIOTBASE)/Makefile.base MODULE=$@
+	$(QQ)"$(MAKE)" -C $(PDIR)/porting/npl/riot/src/ -f $(RIOTPKG)/$(PKG_NAME)/nimble.npl.mk MODULE=$@
 
 # generic modules
 nimble_transport:
diff --git a/pkg/nimble/Makefile.dep b/pkg/nimble/Makefile.dep
index 305bab9c6a..0e25b7851e 100644
--- a/pkg/nimble/Makefile.dep
+++ b/pkg/nimble/Makefile.dep
@@ -3,8 +3,6 @@ USEMODULE += sema
 USEMODULE += event_callback
 USEMODULE += ztimer_msec
 
-USEPKG += nrfx
-
 # Requires nimble feature
 FEATURES_REQUIRED += ble_nimble
 
diff --git a/pkg/nimble/nimble.npl.mk b/pkg/nimble/nimble.npl.mk
new file mode 100644
index 0000000000..ae8b68775a
--- /dev/null
+++ b/pkg/nimble/nimble.npl.mk
@@ -0,0 +1,7 @@
+ifeq (,$(filter nrf51 nrf52 nrf53,$(CPU_FAM)))
+  # nrf5x_isr.c does only compile for nRF5x MCUs
+  IGNORE := nrf5x_isr.c
+  SRC := $(filter-out $(IGNORE),$(wildcard *.c))
+endif
+
+include $(RIOTBASE)/Makefile.base
diff --git a/pkg/nimble/nimble.porting.mk b/pkg/nimble/nimble.porting.mk
index 84cb2c3609..afb6086e77 100644
--- a/pkg/nimble/nimble.porting.mk
+++ b/pkg/nimble/nimble.porting.mk
@@ -1,5 +1,9 @@
 ifneq (,$(filter mynewt-core,$(USEMODULE)))
   SRC = nimble_port.c
+else ifeq (,$(filter nrf51 nrf52 nrf53,$(CPU_FAM)))
+  # hal_timer.c does only compile for nRF5x MCUs
+  IGNORE := hal_timer.c
+  SRC := $(filter-out $(IGNORE),$(wildcard *.c))
 endif
 
 include $(RIOTBASE)/Makefile.base