diff --git a/drivers/include/rn2xx3.h b/drivers/include/rn2xx3.h
index f3023bb3f5..3ccfa68e62 100644
--- a/drivers/include/rn2xx3.h
+++ b/drivers/include/rn2xx3.h
@@ -23,7 +23,7 @@
 
 #include <stdint.h>
 
-#include "xtimer.h"
+#include "ztimer.h"
 #include "periph/uart.h"
 #include "periph/gpio.h"
 #include "net/netdev.h"
@@ -189,7 +189,7 @@ typedef struct {
     uint16_t rx_size;                  /**< counter for received char in RX */
 
     /* timers */
-    xtimer_t sleep_timer;              /**< Timer used to count module sleep time */
+    ztimer_t sleep_timer;              /**< Timer used to count module sleep time */
     uint32_t sleep;                    /**< module sleep duration */
 } rn2xx3_t;
 
diff --git a/drivers/rn2xx3/Kconfig b/drivers/rn2xx3/Kconfig
index a8882fc4dc..b001faca58 100644
--- a/drivers/rn2xx3/Kconfig
+++ b/drivers/rn2xx3/Kconfig
@@ -30,7 +30,8 @@ config MODULE_RN2XX3
     select MODULE_PERIPH_GPIO
     select MODULE_PERIPH_UART
     select MODULE_FMT
-    select MODULE_XTIMER
+    select MODULE_ZTIMER
+    select MODULE_ZTIMER_MSEC
 
 endif # TEST_KCONFIG
 
diff --git a/drivers/rn2xx3/Makefile.dep b/drivers/rn2xx3/Makefile.dep
index 5dbe14d326..a3f5cf86e0 100644
--- a/drivers/rn2xx3/Makefile.dep
+++ b/drivers/rn2xx3/Makefile.dep
@@ -1,4 +1,5 @@
 FEATURES_REQUIRED += periph_gpio
 FEATURES_REQUIRED += periph_uart
-USEMODULE += xtimer
+USEMODULE += ztimer
+USEMODULE += ztimer_msec
 USEMODULE += fmt
diff --git a/drivers/rn2xx3/include/rn2xx3_params.h b/drivers/rn2xx3/include/rn2xx3_params.h
index c28ca1cbb3..3bae65682a 100644
--- a/drivers/rn2xx3/include/rn2xx3_params.h
+++ b/drivers/rn2xx3/include/rn2xx3_params.h
@@ -19,6 +19,7 @@
 #ifndef RN2XX3_PARAMS_H
 #define RN2XX3_PARAMS_H
 
+#include "board.h"
 #include "rn2xx3.h"
 
 #ifdef __cplusplus
diff --git a/drivers/rn2xx3/rn2xx3.c b/drivers/rn2xx3/rn2xx3.c
index b2cc2e5962..180808c33a 100644
--- a/drivers/rn2xx3/rn2xx3.c
+++ b/drivers/rn2xx3/rn2xx3.c
@@ -22,7 +22,7 @@
 #include <errno.h>
 
 #include "assert.h"
-#include "xtimer.h"
+#include "ztimer.h"
 #include "fmt.h"
 #include "kernel_defines.h"
 
@@ -40,7 +40,7 @@
 /**
  * @brief   Delay when resetting the device, 10ms
  */
-#define RESET_DELAY     (10UL * US_PER_MS)
+#define RESET_DELAY     (10UL)
 
 /*
  * Interrupt callbacks
@@ -166,7 +166,7 @@ int rn2xx3_init(rn2xx3_t *dev)
     /* if reset pin is connected, do a hardware reset */
     if (gpio_is_valid(dev->p.pin_reset)) {
         gpio_clear(dev->p.pin_reset);
-        xtimer_usleep(RESET_DELAY);
+        ztimer_sleep(ZTIMER_MSEC, RESET_DELAY);
         gpio_set(dev->p.pin_reset);
     }
 
@@ -233,7 +233,7 @@ int rn2xx3_sys_sleep(rn2xx3_t *dev)
 
     /* Wait a little to check if the device could go to sleep. No answer means
        it worked. */
-    xtimer_msleep(1);
+    ztimer_sleep(ZTIMER_MSEC, 1);
 
     DEBUG("[rn2xx3] RESP: %s\n", dev->resp_buf);
     if (rn2xx3_process_response(dev) == RN2XX3_ERR_INVALID_PARAM) {
@@ -242,7 +242,7 @@ int rn2xx3_sys_sleep(rn2xx3_t *dev)
     }
 
     rn2xx3_set_internal_state(dev, RN2XX3_INT_STATE_SLEEP);
-    xtimer_set(&dev->sleep_timer, dev->sleep * US_PER_MS);
+    ztimer_set(ZTIMER_MSEC, &dev->sleep_timer, dev->sleep);
 
     return RN2XX3_OK;
 }
diff --git a/drivers/rn2xx3/rn2xx3_internal.c b/drivers/rn2xx3/rn2xx3_internal.c
index a0556e2d0d..aca097dafa 100644
--- a/drivers/rn2xx3/rn2xx3_internal.c
+++ b/drivers/rn2xx3/rn2xx3_internal.c
@@ -22,6 +22,9 @@
 #include <string.h>
 
 #include "fmt.h"
+#include "timex.h"
+#include "ztimer.h"
+
 #include "rn2xx3_internal.h"
 
 #define ENABLE_DEBUG 0
@@ -51,22 +54,21 @@ static bool _wait_reply(rn2xx3_t *dev, uint8_t timeout)
     dev->resp_size = 0;
     dev->resp_buf[0] = 0;
 
-    xtimer_ticks64_t sent_time = xtimer_now64();
+    ztimer_now_t sent_time = ztimer_now(ZTIMER_MSEC);
 
-    xtimer_t resp_timer;
+    ztimer_t resp_timer;
     resp_timer.callback = isr_resp_timeout;
     resp_timer.arg = dev;
 
-    xtimer_set(&resp_timer, (uint32_t)timeout * US_PER_SEC);
+    ztimer_set(ZTIMER_MSEC, &resp_timer, (uint32_t)timeout * MS_PER_SEC);
 
     /* wait for results */
     while ((!dev->resp_done) &&
-           xtimer_less(xtimer_diff32_64(xtimer_now64(), sent_time),
-                                        xtimer_ticks_from_usec(timeout * US_PER_SEC))) {
+        ((int32_t)(sent_time + (timeout * MS_PER_SEC) - ztimer_now(ZTIMER_MSEC)) > 0)) {
         mutex_lock(&(dev->resp_lock));
     }
 
-    xtimer_remove(&resp_timer);
+    ztimer_remove(ZTIMER_MSEC, &resp_timer);
 
     if (dev->resp_done == 0) {
         DEBUG("[rn2xx3] response timeout\n");