diff --git a/Makefile.include b/Makefile.include
index 055968e430..546b8485cb 100644
--- a/Makefile.include
+++ b/Makefile.include
@@ -461,6 +461,11 @@ else
   include $(RIOTMAKE)/dependency_resolution.inc.mk
 endif
 
+# Include dfu-util configuration when using riotboot_dfu bootloader before
+# including the board's Makefile.include which could define dfu-util
+# configuration for other DFU bootloaders in use.
+include $(RIOTMAKE)/boot/riotboot_dfu-util.mk
+
 # Include Board and CPU configuration
 INCLUDES += $(addprefix -I,$(wildcard $(BOARDDIR)/include))
 include $(BOARDDIR)/Makefile.include
diff --git a/makefiles/boot/riotboot_dfu-util.mk b/makefiles/boot/riotboot_dfu-util.mk
new file mode 100644
index 0000000000..457fe53a80
--- /dev/null
+++ b/makefiles/boot/riotboot_dfu-util.mk
@@ -0,0 +1,10 @@
+ifneq (,$(filter usbus_dfu,$(USEMODULE)))
+  ifeq (,$(filter riotboot_usb_dfu,$(USEMODULE)))
+    # If module usbus_dfu is used but not module riotboot_usb_dfu, the
+    # application uses DFU Runtime and dfu-util as programmer to flash the
+    # application with the bootloader riotboot_dfu which uses the VID/PID pair
+    # allocated for the RIOT bootloader https://pid.codes/1209/7D02/
+    DFU_USB_ID ?= 1209:7d02
+    DFU_USE_DFUSE ?= 0
+  endif
+endif