diff --git a/makefiles/pseudomodules.inc.mk b/makefiles/pseudomodules.inc.mk
index 063eb10722..c2a03b2d4a 100644
--- a/makefiles/pseudomodules.inc.mk
+++ b/makefiles/pseudomodules.inc.mk
@@ -152,6 +152,7 @@ PSEUDOMODULES += sock_udp
 PSEUDOMODULES += socket_zep_hello
 PSEUDOMODULES += soft_uart_modecfg
 PSEUDOMODULES += stdin
+PSEUDOMODULES += stdio_available
 PSEUDOMODULES += stdio_cdc_acm
 PSEUDOMODULES += stdio_ethos
 PSEUDOMODULES += stdio_uart_rx
diff --git a/makefiles/stdio.inc.mk b/makefiles/stdio.inc.mk
index 63f4ec8e86..477bb6d97e 100644
--- a/makefiles/stdio.inc.mk
+++ b/makefiles/stdio.inc.mk
@@ -17,6 +17,7 @@ endif
 ifneq (,$(filter stdio_cdc_acm,$(USEMODULE)))
   USEMODULE += usbus_cdc_acm
   USEMODULE += isrpipe
+  USEMODULE += stdio_available
 endif
 
 ifneq (,$(filter stdio_rtt,$(USEMODULE)))
@@ -37,6 +38,7 @@ endif
 ifneq (,$(filter stdio_uart_rx,$(USEMODULE)))
   USEMODULE += isrpipe
   USEMODULE += stdio_uart
+  USEMODULE += stdio_available
 endif
 
 ifneq (,$(filter stdio_uart,$(USEMODULE)))
diff --git a/sys/Kconfig.stdio b/sys/Kconfig.stdio
index f031cb0f43..b204e9b0fd 100644
--- a/sys/Kconfig.stdio
+++ b/sys/Kconfig.stdio
@@ -49,10 +49,16 @@ config MODULE_STDIO_UART_RX
     bool
     depends on MODULE_STDIO_UART
     select MODULE_ISRPIPE
+    select MODULE_STDIO_AVAILABLE
     default y if MODULE_STDIN
     help
         Reception when using UART-based STDIO needs to be enabled.
 
+config MODULE_STDIO_AVAILABLE
+    bool
+    help
+        Indicates that the implementation supports function stdio_available
+
 config MODULE_PRINTF_FLOAT
     bool "Float support in printf"
 
diff --git a/sys/include/stdio_base.h b/sys/include/stdio_base.h
index e76bd2ff19..d9a972064f 100644
--- a/sys/include/stdio_base.h
+++ b/sys/include/stdio_base.h
@@ -25,6 +25,8 @@
 
 #include <unistd.h>
 
+#include "kernel_defines.h"
+
 #ifdef __cplusplus
 extern "C" {
 #endif
@@ -34,6 +36,18 @@ extern "C" {
  */
 void stdio_init(void);
 
+#if IS_USED(MODULE_STDIO_AVAILABLE) || DOXYGEN
+/**
+ * @brief   Get the number of bytes available for reading from stdio.
+ *
+ * @warning This function is only available if the implementation supports
+ *          it and the @c stdio_available module is enabled.
+ *
+ * @return  number of available bytes
+ */
+int stdio_available(void);
+#endif
+
 /**
  * @brief read @p len bytes from stdio uart into @p buffer
  *
diff --git a/sys/stdio_uart/stdio_uart.c b/sys/stdio_uart/stdio_uart.c
index 21f715be5b..be6cd8e9b7 100644
--- a/sys/stdio_uart/stdio_uart.c
+++ b/sys/stdio_uart/stdio_uart.c
@@ -67,6 +67,13 @@ void stdio_init(void)
 #endif
 }
 
+#if IS_USED(MODULE_STDIO_AVAILABLE)
+int stdio_available(void)
+{
+    return tsrb_avail(&stdio_uart_isrpipe.tsrb);
+}
+#endif
+
 ssize_t stdio_read(void* buffer, size_t count)
 {
 #ifdef MODULE_STDIO_UART_RX
diff --git a/sys/usb/usbus/cdc/acm/Kconfig b/sys/usb/usbus/cdc/acm/Kconfig
index 68a8ea1d1f..42c2866452 100644
--- a/sys/usb/usbus/cdc/acm/Kconfig
+++ b/sys/usb/usbus/cdc/acm/Kconfig
@@ -58,5 +58,6 @@ config MODULE_STDIO_CDC_ACM
     bool "CDC ACM"
     depends on MODULE_USBUS_CDC_ACM
     select MODULE_ISRPIPE
+    select MODULE_STDIO_AVAILABLE
 
 endchoice
diff --git a/sys/usb/usbus/cdc/acm/cdc_acm_stdio.c b/sys/usb/usbus/cdc/acm/cdc_acm_stdio.c
index 568eddf703..a145b03412 100644
--- a/sys/usb/usbus/cdc/acm/cdc_acm_stdio.c
+++ b/sys/usb/usbus/cdc/acm/cdc_acm_stdio.c
@@ -51,6 +51,13 @@ void stdio_init(void)
 #endif
 }
 
+#if IS_USED(MODULE_STDIO_AVAILABLE)
+int stdio_available(void)
+{
+    return tsrb_avail(&_cdc_stdio_isrpipe.tsrb);
+}
+#endif
+
 ssize_t stdio_read(void* buffer, size_t len)
 {
     (void)buffer;