diff --git a/cpu/sam0_common/include/periph_cpu_common.h b/cpu/sam0_common/include/periph_cpu_common.h
index 9e992b1843..0bad87b265 100644
--- a/cpu/sam0_common/include/periph_cpu_common.h
+++ b/cpu/sam0_common/include/periph_cpu_common.h
@@ -56,6 +56,11 @@ extern "C" {
 #define PERIPH_I2C_NEED_WRITE_REGS
 /** @} */
 
+/**
+ * @brief   Maximum bytes per frame for I2C operations
+ */
+#define PERIPH_I2C_MAX_BYTES_PER_FRAME 256
+
 /**
  * @brief   Override GPIO type
  * @{