diff --git a/sys/net/gnrc/network_layer/ipv6/nib/nib_pl.c b/sys/net/gnrc/network_layer/ipv6/nib/nib_pl.c
index 720ee6a976..312e303b38 100644
--- a/sys/net/gnrc/network_layer/ipv6/nib/nib_pl.c
+++ b/sys/net/gnrc/network_layer/ipv6/nib/nib_pl.c
@@ -69,7 +69,9 @@ int gnrc_ipv6_nib_pl_set(unsigned iface,
         (ipv6_addr_match_prefix(&netif->ipv6.addrs[idx], pfx) >= pfx_len)) {
         dst->flags |= _PFX_ON_LINK;
     }
-    if (netif->ipv6.aac_mode & GNRC_NETIF_AAC_AUTO) {
+
+    /* Auto-configuration only works if the prefix is more than a single address */
+    if ((netif->ipv6.aac_mode & GNRC_NETIF_AAC_AUTO) && (pfx_len < 128)) {
         dst->flags |= _PFX_SLAAC;
     }
 #if IS_ACTIVE(CONFIG_GNRC_IPV6_NIB_6LBR) && IS_ACTIVE(CONFIG_GNRC_IPV6_NIB_MULTIHOP_P6C)