diff --git a/makefiles/stdio.inc.mk b/makefiles/stdio.inc.mk
index e641523145..9749c34177 100644
--- a/makefiles/stdio.inc.mk
+++ b/makefiles/stdio.inc.mk
@@ -82,7 +82,7 @@ endif
 
 # enable stdout buffering for modules that benefit from sending out buffers in larger chunks
 ifneq (,$(filter picolibc,$(USEMODULE)))
-  ifneq (,$(filter stdio_cdc_acm stdio_ethos slipdev_stdio stdio_semihosting,$(USEMODULE)))
+  ifneq (,$(filter stdio_cdc_acm stdio_ethos slipdev_stdio stdio_semihosting stdio_tinyusb_cdc_acm,$(USEMODULE)))
     USEMODULE += picolibc_stdout_buffered
   endif
 endif