diff --git a/tests/sys/ztimer_overhead/Makefile b/tests/sys/ztimer_overhead/Makefile
index 5262b67db3..54e8a91fd1 100644
--- a/tests/sys/ztimer_overhead/Makefile
+++ b/tests/sys/ztimer_overhead/Makefile
@@ -9,4 +9,8 @@ USEMODULE += ztimer_usec
 # microbit qemu timing is off
 TEST_ON_CI_BLACKLIST += microbit
 
+# The test is sensitive to background CPU load. On the CI workers a lot of
+# compilation tasks are run in parallel, making this test randomly fail.
+TEST_ON_CI_BLACKLIST += native
+
 include $(RIOTBASE)/Makefile.include