diff --git a/pkg/tinyusb/hw/hw_stm32_otg.c b/pkg/tinyusb/hw/hw_stm32_otg.c
index 3f1916088e..115ea26e63 100644
--- a/pkg/tinyusb/hw/hw_stm32_otg.c
+++ b/pkg/tinyusb/hw/hw_stm32_otg.c
@@ -37,6 +37,11 @@ static int tinyusb_hw_init_dev(const dwc2_usb_otg_fshs_config_t *conf)
     PWR->CR2 |= PWR_CR2_USV;
 #endif /* PWR_CR2_USV */
 
+#if defined(PWR_SVMCR_USV)
+    /* on U5: Validate USB Supply */
+    PWR->SVMCR |= PWR_SVMCR_USV;
+#endif /* PWR_SVMCR_USV */
+
     /* Enable the clock to the peripheral */
     periph_clk_en(conf->ahb, conf->rcc_mask);