diff --git a/boards/nucleo-l452re/Kconfig b/boards/nucleo-l452re/Kconfig
index b179e4f18a..d6b73dfa7e 100644
--- a/boards/nucleo-l452re/Kconfig
+++ b/boards/nucleo-l452re/Kconfig
@@ -15,6 +15,7 @@ config BOARD_NUCLEO_L452RE
     select CPU_MODEL_STM32L452RE
 
     # Put defined MCU peripherals here (in alphabetical order)
+    select HAS_PERIPH_I2C
     select HAS_PERIPH_PWM
     select HAS_PERIPH_RTC
     select HAS_PERIPH_RTT
diff --git a/boards/nucleo-l452re/Makefile.features b/boards/nucleo-l452re/Makefile.features
index ed7d41364a..726623c2bf 100644
--- a/boards/nucleo-l452re/Makefile.features
+++ b/boards/nucleo-l452re/Makefile.features
@@ -2,6 +2,7 @@ CPU = stm32
 CPU_MODEL = stm32l452re
 
 # Put defined MCU peripherals here (in alphabetical order)
+FEATURES_PROVIDED += periph_i2c
 FEATURES_PROVIDED += periph_pwm
 FEATURES_PROVIDED += periph_rtc
 FEATURES_PROVIDED += periph_rtt
diff --git a/boards/nucleo-l452re/include/periph_conf.h b/boards/nucleo-l452re/include/periph_conf.h
index cd0765c2dc..639e788e5b 100644
--- a/boards/nucleo-l452re/include/periph_conf.h
+++ b/boards/nucleo-l452re/include/periph_conf.h
@@ -27,6 +27,7 @@
 
 #include "periph_cpu.h"
 #include "l4/cfg_clock_80_1.h"
+#include "cfg_i2c1_pb8_pb9.h"
 #include "cfg_rtt_default.h"
 #include "cfg_timer_tim2.h"