diff --git a/tests/periph_cpuid/Makefile b/tests/periph_cpuid/Makefile
index dadc77f857..268f07cd86 100644
--- a/tests/periph_cpuid/Makefile
+++ b/tests/periph_cpuid/Makefile
@@ -3,3 +3,24 @@ include ../Makefile.tests_common
 FEATURES_REQUIRED = periph_cpuid
 
 include $(RIOTBASE)/Makefile.include
+
+# Determine the CPUID_LEN based on the current architecture or CPU used in the
+# build system.
+ifneq (,$(filter arch_esp32,$(FEATURES_USED)))
+  CPUID_LEN = 7
+endif
+ifneq (,$(filter cc2538 efm32 ezr32wg nrf5%,$(CPU)))
+  CPUID_LEN = 8
+endif
+ifneq (,$(filter cc26x0 lpc1768 sam%,$(CPU)))
+  CPUID_LEN = 16
+endif
+ifneq (,$(filter fe310 kinetis stm32%,$(CPU)))
+  CPUID_LEN = 12
+endif
+
+# Use 4 as default as it is the minimum for all supported CPUs.
+CPUID_LEN ?= 4
+
+# Export CPUID_LEN env variable to the Python script.
+export CPUID_LEN
diff --git a/tests/periph_cpuid/tests/01-run.py b/tests/periph_cpuid/tests/01-run.py
new file mode 100755
index 0000000000..3deb058bf8
--- /dev/null
+++ b/tests/periph_cpuid/tests/01-run.py
@@ -0,0 +1,25 @@
+#!/usr/bin/env python3
+
+# Copyright (C) 2019 Inria
+#
+# This file is subject to the terms and conditions of the GNU Lesser
+# General Public License v2.1. See the file LICENSE in the top level
+# directory for more details.
+
+import os
+import sys
+from testrunner import run
+
+
+CPUID_LEN = int(os.getenv('CPUID_LEN') or 4)
+
+
+def testfunc(child):
+    child.expect_exact('Test for the CPUID driver')
+    child.expect_exact('This test is reading out the CPUID of the platforms CPU')
+    expected = 'CPUID:' + CPUID_LEN * r' 0x[0-9a-fA-F]{2}'
+    child.expect(expected)
+
+
+if __name__ == "__main__":
+    sys.exit(run(testfunc))