diff --git a/sys/include/usb/usbus/cdc/acm.h b/sys/include/usb/usbus/cdc/acm.h
index 8bd2f09c48..6eba372af3 100644
--- a/sys/include/usb/usbus/cdc/acm.h
+++ b/sys/include/usb/usbus/cdc/acm.h
@@ -46,15 +46,28 @@ extern "C" {
  * @brief Buffer size for STDIN and STDOUT data to and from USB when using
  *        the USBUS_CDC_ACM_STDIO module
  */
-#ifndef USBUS_CDC_ACM_STDIO_BUF_SIZE
-#define USBUS_CDC_ACM_STDIO_BUF_SIZE (128)
+#ifdef CONFIG_USBUS_CDC_ACM_STDIO_BUF_SIZE_EXP
+#define CONFIG_USBUS_CDC_ACM_STDIO_BUF_SIZE (1<<CONFIG_USBUS_CDC_ACM_STDIO_BUF_SIZE_EXP)
+#endif
+#ifndef CONFIG_USBUS_CDC_ACM_STDIO_BUF_SIZE
+#define CONFIG_USBUS_CDC_ACM_STDIO_BUF_SIZE (128)
 #endif
 
 /**
  * @brief USB CDC ACM bulk endpoint size
  */
-#ifndef USBUS_CDC_ACM_BULK_EP_SIZE
-#define USBUS_CDC_ACM_BULK_EP_SIZE    (64)
+#if IS_ACTIVE(CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE_8)
+#define CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE     (8)
+#elif IS_ACTIVE(CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE_16)
+#define CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE    (16)
+#elif IS_ACTIVE(CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE_32)
+#define CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE    (32)
+#elif IS_ACTIVE(CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE_64)
+#define CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE    (64)
+#endif
+
+#ifndef CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE
+#define CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE    (64)
 #endif
 /** @} */
 
diff --git a/sys/usb/usbus/Kconfig b/sys/usb/usbus/Kconfig
index afeeeceec5..b28fd6016f 100644
--- a/sys/usb/usbus/Kconfig
+++ b/sys/usb/usbus/Kconfig
@@ -42,4 +42,6 @@ config USBUS_EP0_SIZE_64
 
 endchoice
 
+rsource "cdc/Kconfig"
+
 endif # KCONFIG_MODULE_USBUS
diff --git a/sys/usb/usbus/cdc/Kconfig b/sys/usb/usbus/cdc/Kconfig
new file mode 100644
index 0000000000..71eff61702
--- /dev/null
+++ b/sys/usb/usbus/cdc/Kconfig
@@ -0,0 +1 @@
+rsource "acm/Kconfig"
diff --git a/sys/usb/usbus/cdc/acm/Kconfig b/sys/usb/usbus/cdc/acm/Kconfig
new file mode 100644
index 0000000000..0c6c6f1a4d
--- /dev/null
+++ b/sys/usb/usbus/cdc/acm/Kconfig
@@ -0,0 +1,46 @@
+# Copyright (c) 2020 HAW Hamburg
+#
+# This file is subject to the terms and conditions of the GNU Lesser
+# General Public License v2.1. See the file LICENSE in the top level
+# directory for more details.
+#
+menuconfig KCONFIG_MODULE_USBUS_CDC_ACM
+    bool "Configure USBUS CDC ACM"
+    depends on MODULE_USBUS_CDC_ACM
+    help
+        Configure the USBUS CDC ACM module via Kconfig.
+
+if KCONFIG_MODULE_USBUS_CDC_ACM
+
+config USBUS_CDC_ACM_STDIO_BUF_SIZE_EXP
+    int "Buffer size for STDIN and STDOUT data (as exponent of 2^n)"
+    default 7
+    range 0 31
+    depends on MODULE_STDIO_CDC_ACM
+    help
+        As buffer size ALWAYS needs to be power of two, this changes this option
+        represents the exponent of 2^n, which will be used as the size of the
+        buffer.
+
+choice
+    bool "USB CDC ACM bulk endpoint size"
+    default USBUS_CDC_ACM_BULK_EP_SIZE_64
+    help
+        This configures the maximum amount of bytes (chars) sent per transfer
+        over the USB connection.
+
+config USBUS_CDC_ACM_BULK_EP_SIZE_8
+    bool "8"
+
+config USBUS_CDC_ACM_BULK_EP_SIZE_16
+    bool "16"
+
+config USBUS_CDC_ACM_BULK_EP_SIZE_32
+    bool "32"
+
+config USBUS_CDC_ACM_BULK_EP_SIZE_64
+    bool "64"
+
+endchoice
+
+endif # KCONFIG_MODULE_USBUS_CDC_ACM
diff --git a/sys/usb/usbus/cdc/acm/cdc_acm.c b/sys/usb/usbus/cdc/acm/cdc_acm.c
index df79b99b0c..fd9ed9eae2 100644
--- a/sys/usb/usbus/cdc/acm/cdc_acm.c
+++ b/sys/usb/usbus/cdc/acm/cdc_acm.c
@@ -232,14 +232,14 @@ static void _init(usbus_t *usbus, usbus_handler_t *handler)
     usbus_enable_endpoint(ep);
     ep = usbus_add_endpoint(usbus, &cdcacm->iface_data,
                             USB_EP_TYPE_BULK, USB_EP_DIR_IN,
-                            USBUS_CDC_ACM_BULK_EP_SIZE);
+                            CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE);
     ep->interval = 0; /* Interval is not used with bulk endpoints */
     usbus_enable_endpoint(ep);
     /* Store the endpoint reference to activate it
      * when DTE present is signalled by the host */
     ep = usbus_add_endpoint(usbus, &cdcacm->iface_data,
                             USB_EP_TYPE_BULK, USB_EP_DIR_OUT,
-                            USBUS_CDC_ACM_BULK_EP_SIZE);
+                            CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE);
     ep->interval = 0; /* Interval is not used with bulk endpoints */
     usbus_enable_endpoint(ep);
 
@@ -319,12 +319,12 @@ static void _handle_in(usbus_cdcacm_device_t *cdcacm,
         (cdcacm->state != USBUS_CDC_ACM_LINE_STATE_DTE)) {
         return;
     }
-    /* copy at most USBUS_CDC_ACM_BULK_EP_SIZE chars from input into ep->buf */
+    /* copy at most CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE chars from input into ep->buf */
     unsigned old = irq_disable();
     while (!tsrb_empty(&cdcacm->tsrb)) {
         int c = tsrb_get_one(&cdcacm->tsrb);
         ep->buf[cdcacm->occupied++] = (uint8_t)c;
-        if (cdcacm->occupied >= USBUS_CDC_ACM_BULK_EP_SIZE) {
+        if (cdcacm->occupied >= CONFIG_USBUS_CDC_ACM_BULK_EP_SIZE) {
             break;
         }
     }
diff --git a/sys/usb/usbus/cdc/acm/cdc_acm_stdio.c b/sys/usb/usbus/cdc/acm/cdc_acm_stdio.c
index a14dc1a073..9b133c15e8 100644
--- a/sys/usb/usbus/cdc/acm/cdc_acm_stdio.c
+++ b/sys/usb/usbus/cdc/acm/cdc_acm_stdio.c
@@ -38,8 +38,8 @@
 #endif
 
 static usbus_cdcacm_device_t cdcacm;
-static uint8_t _cdc_tx_buf_mem[USBUS_CDC_ACM_STDIO_BUF_SIZE];
-static uint8_t _cdc_rx_buf_mem[USBUS_CDC_ACM_STDIO_BUF_SIZE];
+static uint8_t _cdc_tx_buf_mem[CONFIG_USBUS_CDC_ACM_STDIO_BUF_SIZE];
+static uint8_t _cdc_rx_buf_mem[CONFIG_USBUS_CDC_ACM_STDIO_BUF_SIZE];
 static isrpipe_t _cdc_stdio_isrpipe = ISRPIPE_INIT(_cdc_rx_buf_mem);
 
 void stdio_init(void)