diff --git a/pkg/qDSA/Makefile.include b/pkg/qDSA/Makefile.include
index d7ac128477..6d399ef6c2 100644
--- a/pkg/qDSA/Makefile.include
+++ b/pkg/qDSA/Makefile.include
@@ -11,3 +11,9 @@ endif
 export QDSA_IMPL
 
 INCLUDES += -I$(PKGDIRBASE)/qDSA/$(QDSA_IMPL)
+
+ifeq (cortex-m0plus,$(CPU_ARCH))
+  # There are problems with the LLVM assembler and the Cortex-M0+ instruction
+  # set with this package
+  TOOLCHAINS_BLACKLIST += llvm
+endif