diff --git a/sys/include/net/gnrc/sixlowpan/frag/vrb.h b/sys/include/net/gnrc/sixlowpan/frag/vrb.h
index 61d7a5d486..b1923d8026 100644
--- a/sys/include/net/gnrc/sixlowpan/frag/vrb.h
+++ b/sys/include/net/gnrc/sixlowpan/frag/vrb.h
@@ -75,6 +75,28 @@ gnrc_sixlowpan_frag_vrb_t *gnrc_sixlowpan_frag_vrb_add(
         const gnrc_sixlowpan_frag_rb_base_t *base,
         gnrc_netif_t *out_netif, const uint8_t *out_dst, size_t out_dst_len);
 
+/**
+ * @brief   Generate reassembly buffer from a header's forwarding information.
+ *
+ * @param[in] base  Base data of the datagram. Must not be `NULL`.
+ * @param[in] netif Restict route to this interface. May be `NULL` for any
+ *                  interface.
+ * @param[in] hdr   Header from which to take the forwarding information from
+ *                  (e.g. IPv6 header implies `hdr->type == GNRC_NETTYPE_IPV6`).
+ *
+ * @pre `base != NULL`
+ * @pre `(hdr != NULL) && (hdr->data != NULL) && (hdr->size > 0)`
+ *
+ * @return  The VRB entry pointing to the next hop based on the forwarding
+ *          information provided in @p hdr and present in the respective
+ *          forwarding information base for `hdr->type`.
+ * @return  NULL, if VRB is full or if there is no route to destination in
+ *          @p hdr.
+ */
+gnrc_sixlowpan_frag_vrb_t *gnrc_sixlowpan_frag_vrb_from_route(
+            const gnrc_sixlowpan_frag_rb_base_t *base,
+            gnrc_netif_t *netif, const gnrc_pktsnip_t *hdr);
+
 /**
  * @brief   Checks timeouts and removes entries if necessary
  */
diff --git a/sys/net/gnrc/network_layer/sixlowpan/frag/vrb/gnrc_sixlowpan_frag_vrb.c b/sys/net/gnrc/network_layer/sixlowpan/frag/vrb/gnrc_sixlowpan_frag_vrb.c
index 8c091bcb31..cf6f1bfdc5 100644
--- a/sys/net/gnrc/network_layer/sixlowpan/frag/vrb/gnrc_sixlowpan_frag_vrb.c
+++ b/sys/net/gnrc/network_layer/sixlowpan/frag/vrb/gnrc_sixlowpan_frag_vrb.c
@@ -14,6 +14,11 @@
  */
 
 #include "net/ieee802154.h"
+#ifdef MODULE_GNRC_IPV6_NIB
+#include "net/ipv6/addr.h"
+#include "net/gnrc/ipv6/nib.h"
+#endif  /* MODULE_GNRC_IPV6_NIB */
+#include "net/gnrc/netif.h"
 #include "xtimer.h"
 
 #include "net/gnrc/sixlowpan/frag/vrb.h"
@@ -22,7 +27,11 @@
 #include "debug.h"
 
 static gnrc_sixlowpan_frag_vrb_t _vrb[GNRC_SIXLOWPAN_FRAG_VRB_SIZE];
+#ifdef MODULE_GNRC_IPV6_NIB
+static char addr_str[IPV6_ADDR_MAX_STR_LEN];
+#else   /* MODULE_GNRC_IPV6_NIB */
 static char addr_str[3 * IEEE802154_LONG_ADDRESS_LEN];
+#endif  /* MODULE_GNRC_IPV6_NIB */
 
 #if !defined(MODULE_GNRC_SIXLOWPAN_FRAG) && defined(TEST_SUITES)
 /* mock for e.g. testing */
@@ -91,6 +100,50 @@ gnrc_sixlowpan_frag_vrb_t *gnrc_sixlowpan_frag_vrb_add(
     return vrbe;
 }
 
+gnrc_sixlowpan_frag_vrb_t *gnrc_sixlowpan_frag_vrb_from_route(
+            const gnrc_sixlowpan_frag_rb_base_t *base,
+            gnrc_netif_t *netif, const gnrc_pktsnip_t *hdr)
+{
+    gnrc_sixlowpan_frag_vrb_t *res = NULL;
+
+    assert(base != NULL);
+    assert((hdr != NULL) && (hdr->data != NULL) && (hdr->size > 0));
+    switch (hdr->type) {
+#ifdef MODULE_GNRC_IPV6_NIB
+        case GNRC_NETTYPE_IPV6: {
+            assert(hdr->size >= sizeof(ipv6_hdr_t));
+            const ipv6_addr_t *addr = &((const ipv6_hdr_t *)hdr->data)->dst;
+            gnrc_ipv6_nib_nc_t nce;
+
+            if (!ipv6_addr_is_link_local(addr) &&
+                (gnrc_netif_get_by_ipv6_addr(addr) == NULL) &&
+                (gnrc_ipv6_nib_get_next_hop_l2addr(addr, netif, NULL,
+                                                   &nce) == 0)) {
+
+                DEBUG("6lo vrb: FIB entry for IPv6 destination %s found\n",
+                      ipv6_addr_to_str(addr_str, addr, sizeof(addr_str)));
+                res = gnrc_sixlowpan_frag_vrb_add(
+                        base,
+                        gnrc_netif_get_by_pid(gnrc_ipv6_nib_nc_get_iface(&nce)),
+                        nce.l2addr, nce.l2addr_len
+                    );
+            }
+            else {
+                DEBUG("6lo vrb: no FIB entry for IPv6 destination %s found\n",
+                      ipv6_addr_to_str(addr_str, addr, sizeof(addr_str)));
+            }
+            break;
+        }
+#endif  /* MODULE_GNRC_IPV6_NIB */
+        default:
+            (void)base;
+            (void)netif;
+            DEBUG("6lo vrb: unknown forwarding header type %d\n", hdr->type);
+            break;
+    }
+    return res;
+}
+
 gnrc_sixlowpan_frag_vrb_t *gnrc_sixlowpan_frag_vrb_get(
         const uint8_t *src, size_t src_len, unsigned src_tag)
 {